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ORIGINAL STUDY NON-COMPETITION
Year : 2018  |  Volume : 18  |  Issue : 5  |  Page : 32-33

OSNC9: The effectiveness of Nigella sativa in elimination of Candida Albicans denture biofilms - A pilot study


Date of Web Publication31-Oct-2018

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-4052.244650

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How to cite this article:
... OSNC9: The effectiveness of Nigella sativa in elimination of Candida Albicans denture biofilms - A pilot study. J Indian Prosthodont Soc 2018;18, Suppl S1:32-3

How to cite this URL:
... OSNC9: The effectiveness of Nigella sativa in elimination of Candida Albicans denture biofilms - A pilot study. J Indian Prosthodont Soc [serial online] 2018 [cited 2018 Nov 20];18, Suppl S1:32-3. Available from: http://www.j-ips.org/text.asp?2018/18/5/32/244650



Nur Atikah Mustafa, Noor Ilyani Othman, Siti Nur Atiqah Mohd Kandis, Nurul Surhana Mohd Daud

Faculty of Dentistry, UiTM Sg Buloh Campus, Jalan Hospital, 47000 Sg Buloh, Selangor, Malaysia

Aim: Nigella sativa, one of traditional herbs widely used as supplement, traditional medicine and personal hygiene products. Recently, natural based herbs have become an alternative material used for denture cleansing, thus this study is conducted to identify the efficacy of Nigella sativa on elimination of Candida albicans biofilm from denture base polymer.

Materials and Methods: Thirty sterilized disc shape (10 x 2) mm heat cured denture base polymers (PMMA) were fabricated and divided into three groups (n=10): Group A was immersed in distilled water, Group B was coated within Candida albicans suspension for 24 hours, then Group C had the same procedure as group B, followed by immersion with Nigella sativa seeds extract for 1 hour.

Results: The One-way ANOVA test has revealed that mean number of colony forming unit in Group C was significantly reduced (1.20±10-1) as compared to Group B (5.24±10-1), p< 0.01. Following 24hour immersion in candida suspension, the number of colony forming was increased in group B when compare to Group A, with mean of CFU values p<0.01. However, the results showed there was no significant different between the Group A and Group C, with p>0.01. Further analysis comparing the mean growth scores of each group using post-hoc Dunnet T3 test shows the same results.

Conclusions: The result of this study had presented that Nigella sativa is effective in reducing Candida albicans biofilm colonization on denture base polymer.






 

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