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CASE REPORT NON-COMPETITION
Year : 2018  |  Volume : 18  |  Issue : 5  |  Page : 50-51

CRNC13: Healing large bone defect with concentrated growth factor in window sinus lift: A case report


Date of Web Publication31-Oct-2018

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-4052.244584

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How to cite this article:
... CRNC13: Healing large bone defect with concentrated growth factor in window sinus lift: A case report. J Indian Prosthodont Soc 2018;18, Suppl S1:50-1

How to cite this URL:
... CRNC13: Healing large bone defect with concentrated growth factor in window sinus lift: A case report. J Indian Prosthodont Soc [serial online] 2018 [cited 2018 Dec 15];18, Suppl S1:50-1. Available from: http://www.j-ips.org/text.asp?2018/18/5/50/244584



Sharon Lee Sher Ling

Private Dental Practitioner, Kuala Lumpur, Malaysia

Introduction: Large bone defects usually need large membrane to cover and months for bone maturation. Healing of large bone defect has improved by the use of Concentrated Growth Factor CGF liquid phase mixture with bone graft to increase cell proliferation, and CGF solid phase as membrane to speed up soft tissue healing and maturation therefore leaving inner bone to consolidate.

Case description: Male 55y/o without medical problem require a implant at #14, #25 and #26; CBCT show need of sinus lift on #25 #26 which requiring 9mm of augmentation. 5tube of blood was drawn for CGF; sinus lift was done by lateral window without perforation. One CGF membrane was tuck in to protect membrane layer. 0.5CC allograft mix with CGF liquid phase, bone become sticky and packed without pressure condensation. 2CGF membrane was covered on surface and suture. 2 weeks post-surgery review with excellent soft tissue closure. CBCT 6 months later show well consolidated bone graft with good cortical layer, implant was placed into mature grafted area, and restored with individual crown after 3 months.

Discussion: In large defect, bone grafts are more difficult to survive with varying degree of graft resoption, and tissue tension during closure. CGF contain high quantities of growth fator including TGFB1, VEGF, presence of multipotent hempoietic stem cells CD34+, promoting cells proliferation, ostegenic maturation and tissue regeneration. First CGF membrane placement helps to protect sinus membrane.

Conclusion: Healing is concerning factor for large defect. Therefore, in this case report, CGF was in cooperated to prevent excessive shrinkage and improve survival of graft and tissue.






 

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